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Articles on ACE2

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This antibody adopts a Y-shape. The arms of the Y make up the part of the antibody that binds to the target. ALFRED PASIEKA/SCIENCE PHOTO LIBRARY

One small part of a human antibody has the potential to work as a drug for both prevention and therapy of COVID-19

Antibodies are great for neutralizing viruses. But they are big and bulky. Antibody engineers are now creating smaller synthetic antibody-like molecules that may be better for fighting COVID-19.
A molecular model of the spike proteins (red) of SARS-CoV-2 binding to the angiotensin-converting enzyme 2 (ACE2) protein, the receptor (blue) which is its the entry route to the target cell. Juan Gaertner/Science Photo Library

What is the ACE2 receptor, how is it connected to coronavirus and why might it be key to treating COVID-19? The experts explain

The ACE2 receptor allows the virus that causes COVID-19 to infect and destroy our cells. What is the normal role of ACE2 in the body, and could it be the key to blocking infection?
What would Darwin consider the best adaptation to protect against the coronavirus? rolbos / Getty Images

What does ‘survival of the fittest’ mean in the coronavirus pandemic? Look to the immune system

Who is most likely to survive an infection of the new coronavirus? Two immunologists explain that it is those who mount exactly the right immune response – not too weak, not too strong.
A woman with diabetes monitors her glycemia on the eighth day of a strict lockdown in France aimed at curbing the spread of COVID-19. FRANCK FIFE/AFP via Getty Images

Blood sugar levels may influence vulnerability to coronavirus, and controlling them through conventional means might be protective

What does high blood sugar have to do with vulnerability to COVID-19? And is there a role for the controversial drug hydroxychloroquine in lowering blood sugar in COVID-19 patients?

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