The Food and Drug Administration’s approval of Narcan will make the lifesaving drug more widely available, especially to those who might be likely to witness or respond to opioid overdoses.
Xylazine, or tranq, is increasingly being mixed with drugs like fentanyl or heroin and can be difficult to detect. Most people who use drugs are unable to tell if they have been exposed to it.
Fentanyl’s wide availability in the drug supply has led to an increase in unintentional overdoses. While prevention strategies are available, limited availability stymies their use.
Fentanyl adulteration led to the replacement of heroin in the unregulated drug supply of British Columbia. Now that benzodiazepines are present in many opioids, are we headed towards a ‘new normal?’
Opioid overdoses killed 47,000 Americans in 2017 — more than gun violence. Many fewer would have died if they’d been treated with the life-saving drug naloxone, also called Narcan.
Jonathan S. Jones, Binghamton University, State University of New York
Considered in historical context, Purdue’s plan to peddle opioid addiction medicines to vulnerable people is not so surprising. Gilded-Age pharmaceutical companies used similar strategies.
The toll of the opioid epidemic is often derived from toxicology reports. These rely on drug tests. A medical historian explains these tests and how they fall short of capturing why people are dying.
Cyrus Ahalt, University of California, San Francisco
One study argues that naloxone increases opioid use because it protects against death from overdose. But a closer analysis shows Narcan is the number one public health tool to fight the overdose epidemic.
Opioids kill 100 people each day in the US, more than vehicular accidents. Those addicted are often left without treatment. An addiction researcher offers six steps to address the epidemic.
Catastrophic increases in opioid overdose deaths across Canada require a broad response – tackling housing, food and income insecurity as well as the contaminated drug supply.
Opioids kill an average of eight people every day in Canada. The federal government must officially declare this a ‘public welfare emergency’ and invest the funds critical to a humane response.