The well-used drug clomipramine could target tumour cells and leave normal cells healthy – if scientists could get enough evidence for it.
Taking antidepressants during pregnancy is linked with various health issues, but stopping taking antidepressants can be even more problematic.
Avoiding or delaying diagnosis means people miss out on treatments that might have eased their suffering.
While it's important to increase the diagnosis of depression and find a treatment plan that suits the individual, simply writing more scripts for antidepressants isn't the answer.
Ketamine crystals could help depression, too.
Ketamine may be the latest recreational drug to find a new legal use.
Weighing up risks and benefits.
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Commonly prescribed antidepressants increase the risk of suicidal thoughts in teenagers, so why isn't this a bigger deal in drug trials?
People who believe their problems have biogenetic causes tend to opt for biomedical treatments.
Biological and genetic explanations of mental illness can weaken people’s sense of control and optimism, and create a bias against effective psychological interventions.
Trichotillomania is a psychological disorder that leads people to compulsively and uncontrollably pull out their own hair.
People with trichotillomania often pull to the point of causing complete hair loss even though that's never intended or desired. And this eventually leaves them feeling depressed and isolated.
found significant increases in harms with both the antidpressants used in Study 329, compared to the placebo.
As part of an intiative to re-examine misrepresented or abandoned studies, we re-analysed an antidepressant trial. Here's what we found.
Melancholia may be a distinct type of depression, with its own clinical signs and symptoms.
Melancholia has a strong genetic contribution, so it's largely biologically underpinned rather than caused by social factors (stressors) or psychological factors, such as personality style.
Some welcome the possibility of drugs altering our brain for the better, others are concerned about altering our brains at all.
Scientists seek out drugs to cure what ails us but we now know that some common medications affect our moral capacity. Since it's happening already, the question is, should we be worried?
Women planning a family who abruptly stop using antidepressants may be putting themselves in harm’s way.
Research published today has found an association between commonly used antidepressants and birth defects. But pregnant women face greater harms from stopping their medication abruptly.
Changing views on depression.
New ideas about what depression is and how to treat it are being held back by a lack of commercial interest.
It’s as much about what’s happening in your brain.
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Already widely prescribed as antidepressants, SSRIs such as fluoxetine (the non-brand name for Prozac) have gained increasing acceptance over the past 20 years in the treatment of premenstrual syndrome…
For people with severe depression, incorrect application can worsen their condition or cause memory loss.
Around 350 million people worldwide have depression. Antidepressant medications are often prescribed to treat the condition, alongside talking therapies and lifestyle changes such as regular exercise…
Antidepressants might actually be underprescribed.
There is a persistent media hype surrounding the notion that the prescription of antidepressants is “at record levels”, and “on the rise”. Yet numerous studies have shown that most people with depression…
People who attribute mental illness to brain disease or genes tend to blame affected people less, but see them as more hopeless and dangerous.
Depression, schizophrenia and other psychiatric conditions are increasingly linked to abnormalities in the brain and in our genes. Many professionals believe these developments hold the key to better treatments…
Taking antidepressants during pregnancy does not affect the fetus’ cardiac development, a new study has found. The study…
Ketamine may play a role in preventing suicide and lifting the mood of severely depressed patients, according to a new study…
Women who keep taking their antidepressants while breastfeeding are more likely to breastfeed for the recommended six months…
Amphipods on anti-depressants found their lives brightened, right up until they were eaten.
The idea that tiny amounts of antidepressants present in our rivers and estuaries may be affecting aquatic life is generally met with surprise, sometimes scepticism, or even a degree of humour. The public…