The animal studies are promising but early research in humans show mixed results. Here’s what we know so far.
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Articles on Ozempic
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Does weight come back when you stop taking drugs like Ozempic? Are these medications simply another (expensive) form of yo-yo dieting? Here’s what we know so far.
We don’t tell people taking statins to treat high cholesterol or drugs to manage high blood pressure they’re cheating or taking the easy way out. Nor should we when people take drugs like Ozempic.
Many have declared drugs like Ozempic could ‘end obesity’. This isn’t just untrue – it also perpetuates fat stigma.
In Australia, Ozempic is only approved to treat diabetes but doctors are prescribing it ‘off label’ for weight loss. Compounding pharmacies have also been making their own versions to meet demand.
Ozempic generated A$21 billion of sales in 2023 alone. So how was it developed? And how are its new competitors, Mounjaro and Zepbound, different?
Early on we heard a lot about the potential benefits of drugs like Ozempic. Now we’re hearing more about the risks. But what does the latest evidence say?
Laxatives and stool softeners are not designed to be used for weight loss.
The demand for off-label weight loss drugs like Ozempic is concerning, because of the impact on weight stigma and the health risks of unsupervised weight loss, including developing eating disorders.
The first-ever imaging and recording of a brainstem structure critical for feeling full could help reveal exactly how weight loss drugs like Ozempic work, and how to make them more effective.
Weight loss and diabetes drugs target regulatory pathways involved in metabolism that the microbes in your gut and certain molecules from food already play a key role in regulating.
Medications can play an important role in weight management, but not at the expense of overall nutrition. And healthy lifestyle habits are also key.
Drugs for menopause, ADHD and type 2 diabetes were all in short supply this year.
In trials, Mounjaro was shown to be more effective than Ozempic in managing type 2 diabetes.
Any weight loss is likely to be temporary and long term use may be dangerous.
The Conversation has been following the trials and tribulations of semaglutide (Wegovy) as it made its way from lizard venom to blockbuster drug.
From rat poison to explosives, many of the drugs we use have interesting origin stories.
Weight-loss jabs might help with certain heart conditions, but their benefit is being overstated.
The messaging around Ozempic being a miracle cure is not only a lie, it has kicked up a new level of fatphobia.
Doctors once prescribed overweight people extracts of animal glands – either eaten raw or dried in pill form or injected – to treat their supposedly ‘sluggish glands’.
Top contributors
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Associate Professor of the School of Pharmacy, University of Sydney
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Associate Lecturer, Sydney Pharmacy School, University of Sydney
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Adjunct Senior Lecturer, Nutrition, Dietetics & Food Innovation - School of Health Sciences, UNSW Sydney
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Practice Pharmacist/Honorary Senior Research Fellow, University of Bradford
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Associate Professor of Gastroenterology, School of Medicine, University of Washington
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Director of the Digital Health Enterprise Zone (DHEZ), University of Bradford, Professor of Health Service Operations, University of Bradford
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Lecturer, Pharmacy, Aston University
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Assistant Professor, Critical Disability Studies, Carleton University
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Associate Professor in Pharmacy Practice, University of Bradford
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General Practitioner, PhD Candidate, Bond University
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Lecturer Pharmacy Practice, University of Sydney
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Senior Lecturer in Physiology, Anglia Ruskin University
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DPhil Candidate, Alzheimer's, University of Oxford
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Lecturer of the Sydney Pharmacy School, University of Sydney
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Professor of Exercise Science and Interim Dean of the School of Health Sciences, College of Charleston
