Nearly 50 years old, the treaty has been signed by 190 countries – more than any other arms limitation treaty. But now Iran is threatening to withdraw.
Iranian President Hassan Rouhani staked his political fortunes on bringing Iran out of isolation. Now, it appears he's losing control to hard-liners in Iran.
Iran has announced it will breach the limits on uranium enrichment agreed under the 2015 nuclear deal, after the US turned its back on the agreement. What does that mean for Iran's nuclear program?
Despite the UK's close relationship with Saudi Arabia, the British public think much the same about its global influence as they do about Russia and Iran – and it isn't good.
Iran has long recognised the benefits of using cryptocurrencies to counter US sanctions.
Donald Trump stepped back from launching US airstrikes inside Iran, but the conflict is unabated and there appears to be no way out of confrontation for now.
The US has imposed new sanctions against Iran's top leaders, but its foreign policy has no clear focus.
Trump announced 'hard-hitting' new sanctions on Iran in response to the attack on a US drone. A peace studies scholar explains why sanctions rarely work.
The US isn't the only country considering a military response to Iranian aggression.
Iran's leaders are threatening to breach a 2015 agreement that froze their country's nuclear program. What is uranium enrichment, and what would it mean for Iran's ability to build nuclear weapons?
Recent speeches suggest there may be an appetite for closer relations, but it won't be easy. A Saudi and an Iranian explain.
A showdown with Iran over some oil tanker attacks in the Persian Gulf could push the US into its next Mideast war, writes a scholar of military aggression.
After years of work, the JCPOA nuclear deal could be on its last legs.
Growing fears of a US conflict with Iran show why the kind of unilateral sanctions the Trump administration imposed last year don't work.
Both Iran and the US say they are not seeking a war, but it could happen by default.
A terrorism expert exposes the quirks, inconsistencies and foreign policy strategy behind the State Department's terrorist watchlist.
From May 2, any countries buying oil from Iran can expect US sanctions.
The Syrian civil war has ended, but there are millions of Syrian refugees living in Turkey, Jordan and Lebanon. With danger from a hostile regime back in Syria, what will happen to them now?
The US has supported a Saudi-led military coalition that has inflicted profound and deadly damage on Yemen. A Senate vote could end what a human rights scholar says is US complicity in genocide.
Hostility to Iran's revolution from both the West and in the region is as virulent now as it was in February 1979.