Our understanding of Parkinson’s disease is far from complete. But researchers now believe that in most cases, Parkinson’s is caused by a complex interaction between genetic and environmental factors.
Mitochondria help ensure our cells have the energy they need to function.
Mitochondria, which are found in every cell in the body, play an important role in brain function.
More than eight per cent of study subjects were ‘kinless’ at the time of their dementia diagnosis.
New research affords a rare window into the circumstances and needs of a potentially very vulnerable group that until now has remained largely invisible: people with dementia who have no close kin.
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Alzheimer’s disease in young adults is a rare yet growing phenomenon.
Surprisingly, even packaged foods that contain healthy components can qualify as ultra-processed.
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Researchers are trying to understand whether ultraprocessed foods erode brain health in the aging process.
Mice with minimal levels of gut bacteria showed less brain cell damage.
Though this genetic form of Alzheimer’s only affects around 1% of the population, it provides useful information on how the disease progresses.
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Although autosomal dominant Alzheimer’s disease is very rare, studying it provides researchers with valuable information on how the disease progresses in general.
Many viruses interact with the olfactory system, and can damage other areas of the brain through it.
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Inflammation and damage to the olfactory system from shingles, COVID-19 and herpes infections may contribute to Alzheimer’s disease.
Alzheimer’s disease is an incapacitating, progressive brain disorder that affects the lives of more than 6.5 million Americans.
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In clinical trials, lecanemab slowed disease progression by 27% and reduced the amount of plaque found in the brains of those with Alzheimer’s disease.
Not only is it good aerobic exercise, but dancing may help the elderly with reasoning skills and memory.
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Dancing requires physical, social and cognitive engagement and, as a result, it may bolster a wide network of brain regions.
Lecanemab is an antibody that attaches to beta-amyloid proteins accumulated in the brain and allows the immune system to get rid of them.
An 18-month treatment with lecanemab slows functional and cognitive loss by 27 per cent in people with mild Alzheimer’s disease. But this is only the first step towards a real cure.
The decision to move a loved one with dementia into residential care is an incredibly difficult one. These considerations may help.
Not all memory lapses are due to age-related changes in our brains. You could just be tired, anxious or distracted. Here’s what signals a problem.
Type 2 diabetes, characterised in its advanced stages by insulin resistance, is an important risk factor for Alzheimer’s disease.
Impaired insulin receptors in the blood vessels between the blood and the brain may contribute to the insulin resistance observed in Alzheimer’s disease.
Two new dementia drugs are being hailed as breakthroughs. But what might be an incremental breakthrough for researchers, doesn’t mean a cure for patients.
Microglia (colored green) play several essential roles in maintaining brain health and function.
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Microglia, immune cells disguised as brain cells, are known as the janitors of the brain. Dialing up their usual duties just enough could provide an avenue to treat neurodegenerative disease.
Lecanemab slows progression of early-stage Alzheimer’s disease in some, new study shows. But the ‘adverse events’ are significant.
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With a good diet and rest, we can all reduce our risk of dementia.
Experimental drugs gantenerumab has failed phase 3 clinical trials. Here’s what that means for the future of the amyloid hypothesis.
Around the world 55 million people live with dementia. Researchers are still looking for answers on what causes it and how to treat it.
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The world’s longest running cohort study reveals risk factors for dementia. Families of athletes with early-onset dementia tell their stories. Could viruses cause Alzheimer’s? Listen to the Uncharted Brain: Decoding Dementia podcast series.