A depressive episode traps the patient in a negative view of the world around them.
Approximately 280 million people in the world suffer for depression. Despite this, the disorder remains poorly explained and is often difficult to treat. Ketamine could offer an innovative approach.
What happens when drug testing experts come across a substance they have never seen before?
Some of the positive photos used in the study were similar to this one – a group of smiling strangers.
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In a new study, a single infusion of the antidepressant – along with repeated exposure to positive imagery – significantly reduced symptoms in depressed patients in a clinical trial.
Now restrictions are easing, some people who have not used alcohol or other drugs recently may start to use them again, and need to be aware of their reduced tolerance.
Preventing drink spiking is a collective responsibility, not something to be shouldered by potential victims.
Alleviating major depression for the long term involves more than just drugs.
Rafa Elias via Getty Images
Drugs like ketamine can relieve depression symptoms, including suicidal thoughts, within hours, but they also carry risks that patients need to understand.
Over-activity in the brain’s subgenual anterior cingulate cortex is likely to be one cause of depression and anxiety.
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This brain region also shows how effective certain treatments will be.
Drugs like MDMA, ketamine, LSD and psylocibin may help heal the wounds of trauma - but more research is needed.
Would you put it up your nose?
Ketamine and other psychedelics are being licensed for medical use – two experts advise how to minimise harm for users.
Ketamine is effective for those who do not respond to traditional anti-depressants. It also shows promise for the treatment of PTSD and bipolar disorder.
Research shows that ketamine can produce long-term reductions in symptoms of treatment-resistant depression.
One in 3 people with severe depression do not respond to treatment.
A safety committee convened by the FDA has declared esketamine safe for severe depression. But isn’t this drug the same as ketamine, an illegal street drug? A medical anthropologist explains.
We’ve got better at managing the health risks of traditional drugs of abuse, but novel psychoactive substances, or ‘legal highs’, are a dangerous unknown.
Psychedelic drugs have inspired great songs and works of art. But they may also have potential for treating disease like depression and PTSD by helping to regrow damaged regions of the brain.
Young people have reported cultural gains from drug use, such as strengthening social ties and gaining access to social networks.
A new study among gay and bisexual men living with HIV found those who were occasional or regular users of party drugs reported significantly better social outcomes than non-users.
A small number of people, who probably use other party drugs, use ketamine recreationally.
At higher doses ketamine is used to induce a trance-like state, sedate people with burns or other traumatic injuries, or as an anaesthetic to perform short operations.
LSD causes euphoria, increased body temperature and hallucinations where some or all of the senses are distorted.
During the 1950s and 1960s, LSD was used more for psychotherapy than recreation. Between 1950 and 1965, many were treated with LSD for alcoholism, depression, schizophrenia, autism and homosexuality.
Ketamine crystals could help depression, too.
Ketamine may be the latest recreational drug to find a new legal use.
Ketamine may play a role in preventing suicide and lifting the mood of severely depressed patients, according to a new study…
Younger Chinese revellers are seeking new highs.
The close of 2013 saw a drugs bust of cinematic proportions in China. Part of Operation Thunder, more than 3,000 armed police with a cavalry of helicopters, motorboats and police dogs busted the village…
Except for medical reasons or if you’re a horse.
The Justified Sinner
Sometimes it seems you’ve only got to turn around and there is another drug in the news. Now we are told that ketamine should be upgraded from being a Class C drug to a Class B drug. Why does this matter…