After the failure of multiple drug trials the outlook for an Alzheimer's drug is bleak. This shouldn't be a surprise. We don't know the cause or even how to diagnose the disease.
Not all drug development needs to start from scratch. Sometimes researchers discover that a drug developed for one disease can be used for another. Here a cancer drug may show promise for dementia.
Many pieces leading to Alzheimer's disease have been identified. To put the pieces together, one scholar argues that the government should launch a Manhattan Project-scale effort to find a cure.
Have you noticed your thinking ability drops during winter and spring? A new study of healthy adults and dementia patients found cognitive function declines in the colder months.
Alzheimer's drug development tends to focus on protein aggregates in the brain. Perhaps that's why they've all failed.