Treatments for uncomplicated malaria remain mostly robust. But the arsenal against severe malaria and deaths is rapidly weakening. New options are urgently required.
While ivermectin was originally used to treat river blindness, it has also been repurposed to treat other human parasitic infections.
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Ivermectin has been a lifesaving drug for people with parasitic infections like river blindness and strongyloidiasis. But taking it for COVID-19 may result in the opposite effect.
Chloroquine is an antimalarial drug originally developed in 1934; it doesn’t block coronavirus infection in humans.
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When news reports tout a drug, people get interested, even if the benefits are unproven. Patient hopes, requests and demands can easily turn into real prescriptions in their doctor’s office.
We are slowly figuring out which drugs and therapies are effective against the new coronavirus.
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During the last six months, news reports have mentioned dozens of drugs that may be effective against the new coronavirus. Here we lay out the evidence and reveal which ones are proven to work. Or not.
The World Health Organisation has suspended the use of hydroxychloroquine in a global drug trial.
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The US president has reignited controversy over the use of malaria drugs to guard against COVID-19. But there is little reliable evidence so far that this tactic is safe or effective.
Coronavirus drug trials are underway – a virologist explains what the treatment options may be.
Employees work on the production line of chloroquine phosphate, resumed after a 15-year break, in a pharmaceutical company in Nantong city in east China’s Jiangsu province Thursday, Feb. 27, 2020.
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The president promoted the combination of hydroxychloroquine and an antibiotic for treating COVID-19. But a new study suggests it provides no benefits.
A sample of cinchona bark.
Kim Walker & Harriet Gendall. RBG Kew.
Taking these drugs to treat COVID-19 without medical advice has caused poisonings and death.
An employee in Nantong, China, checks the production of chloroquine phosphate, an old drug for the treatment of malaria.
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A medicinal chemist addresses questions about chloroquine and hydroxychloroquine: what it is, whether it is effective against COVID-19 and whether it can treat and/or prevent this disease.
Professor of Chemistry and Biochemistry and President-Elect of the International Society for Antiviral Research, University of Maryland, Baltimore County