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Articles on Cancer

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Dendritic cells (green) produce cytokines like IL-12, which can train T cells (pink) to attack tumors. Victor Segura Ibarra and Rita Serda/National Cancer Institute via Flickr

‘Masked’ cancer drug stealthily trains immune system to kill tumors while sparing healthy tissues, reducing treatment side effects

One promising cancer treatment has been in the works for decades, but severe side effects have kept it out of the clinic. A reengineered version may offer a way to safely harness its potent effects.
Cancer-causing viruses like HPV can cause cells to divide indefinitely and, in the case of Henrietta Lacks, become immortal. Tom Deerinck/NIH via Flickr

What are HeLa cells? A cancer biologist explains

The immortal cancer cells of Henrietta Lacks revolutionized the fields of science, medicine and bioethics. And they still survive today, more than 70 years after her death.
Identifying the difference between normal genetic variation and disease-causing mutations can sometimes be difficult. Andrii Yalanskyi/iStock via Getty Images Plus

Genetic mutations can be benign or cancerous – a new method to differentiate between them could lead to better treatments

Tumors contain thousands of genetic changes, but only a few are actually cancer-causing. A quicker way to identify these driver mutations could lead to more targeted cancer treatments.
Cancer groundshot highlights that investment in improving access to treatments already proven to work saves more lives than discovery of a new treatment. (Shutterstock)

Cancer groundshot: Access to proven treatments must parallel development of new therapies

Globally, most cancer patients die not because they don’t have access to newer drugs, but because they don’t have access to even basic treatments. Cancer groundshot aims to improve treatment access.
Preclinical research — the kind that takes place before testing on humans — often guides decisions about which potential treatments should continue to clinical trials. But attempts to replicate 50 studies found the odds of getting the same results were only about 50-50. (Pexels/Artem Podrez)

Major study shows the need to improve how scientists approach early-stage cancer research

Preclinical studies are an important part of biomedical research, often guiding future trials in humans. Failure to replicate research results suggests a need to increase the quality of studies.

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