Treatments for uncomplicated malaria remain mostly robust. But the arsenal against severe malaria and deaths is rapidly weakening. New options are urgently required.
Ivermectin has been a lifesaving drug for people with parasitic infections like river blindness and strongyloidiasis. But taking it for COVID-19 may result in the opposite effect.
When news reports tout a drug, people get interested, even if the benefits are unproven. Patient hopes, requests and demands can easily turn into real prescriptions in their doctor’s office.
During the last six months, news reports have mentioned dozens of drugs that may be effective against the new coronavirus. Here we lay out the evidence and reveal which ones are proven to work. Or not.
The US president has reignited controversy over the use of malaria drugs to guard against COVID-19. But there is little reliable evidence so far that this tactic is safe or effective.
The president promoted the combination of hydroxychloroquine and an antibiotic for treating COVID-19. But a new study suggests it provides no benefits.
A medicinal chemist addresses questions about chloroquine and hydroxychloroquine: what it is, whether it is effective against COVID-19 and whether it can treat and/or prevent this disease.
Professor of Chemistry and Biochemistry and President-Elect of the International Society for Antiviral Research, University of Maryland, Baltimore County