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Alzheimer’s disease is characterized by progressive memory loss, spatial disorientation and many other cognitive and behavioural disorders that ultimately lead to a state of total dependence. (Shutterstock)

FDA approval of controversial Alzheimer’s drug could delay discovery of more promising treatments

The new drug is based on the idea that a build-up of amyloid in the brain leads to the disease. But that hypothesis has been under scrutiny lately.
In most cases, scientists are still unsure of what causes Alzheimer’s disease. FGC / Shutterstock.com

No cure for Alzheimer’s disease in my lifetime

After the failure of multiple drug trials the outlook for an Alzheimer’s drug is bleak. This shouldn’t be a surprise. We don’t know the cause or even how to diagnose the disease.
An MRI image of the brain. SpeedKingz/Shutterstock.com

An unexpected pathway to treating neurodegenerative diseases

Not all drug development needs to start from scratch. Sometimes researchers discover that a drug developed for one disease can be used for another. Here a cancer drug may show promise for dementia.
Figuring out the pieces to the Alzheimer’s puzzle. Naeblys/Shutterstock.com

Time for a Manhattan Project on Alzheimer’s

Many pieces leading to Alzheimer’s disease have been identified. To put the pieces together, one scholar argues that the government should launch a Manhattan Project-scale effort to find a cure.

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