The US PEPFAR initiative has brought HIV medication to millions of people globally. Behind this progress are the activists that pressured politicians and companies to put patients over patents.
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Articles on Antiretroviral therapy
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Dec. 1 marks World AIDS Day. Canada has the tools and means to end the epidemic. The question remains, are we up to the task?
The benefit of an injectable product is that it avoids the adherence issues related to taking a pill daily.
When antiretroviral therapy is working effectively, HIV cannot be transmitted. This allows people with HIV to live fuller lives without the fear of infecting others.
Antiretroviral therapies for HIV, while extremely effective, need to be taken daily for life. Designing antibody treatments that need to be taken only once could improve compliance and reduce drug resistance.
Patients with low HIV viral loads are just as likely to harbour HIV variants with drug resistance mutations as those with high viral loads.
The omission of growing evidence that Māori, and Māori women in particular, have worse health outcomes after HIV infection could derail New Zealand’s elimination plans and exacerbate disparities.
We expected to find that screening everybody for TB would identify individuals not yet diagnosed, and treating them quickly would reduce the prevalence of TB in the community.
Unless special attention is given to conflict and HIV the war will undermine the achievement of the 2030 goals to end AIDS, discrimination, and new infections.
HIV services must be comprehensive to ensure that people take their medication as prescribed and avoid onward transmission of the virus.
Even before the advent of COVID-19, donors had begun to exit HIV programmes with increasing frequency.
It is urgent and overdue to implement PrEP in pregnancy and during breastfeeding. Failure to do so allows ongoing avoidable HIV infection among women in South Africa and their infants.
People with HIV need to take daily medication to keep the virus at bay. A study has found that a new treatment combination could boost immunity and control virus levels even after stopping medication.
There are currently 1.2 million Ugandans enrolled on antiretroviral therapy (ART). They are especially affected by the lockdown.
South Africa needs a public health response that expands the successes of the country’s HIV testing and treatment programme to provide care for multiple diseases.
Not achieving the targets for children and adolescents in sub-Saharan Africa means that new infections will continue to increase and HIV related mortality will be a reality for decades to come.
Cryptococcal ceningitis is one of the main causes of death of people with HIV. The tests and medicines to diagnose and treat it exist but remain inaccessible to most. A global strategy is needed.
Where there are not enough health workers to deliver medical care, one solution is to move certain tasks to less specialised health workers, a process called task-shifting.
If the world is single-minded and focuses purely on combating one pandemic, forgetting others, the effects of other morbidity and mortality on healthcare systems will be seen for a long time to come.
Nurses represent 50% of the global healthcare workforce. And they are often the sole healthcare providers in many low and middle-income countries.
The giant leap in the number of people accessing HIV treatment would not have been possible without task shifting from medical doctors to less-specialised cadres such as nurses and midwives.
Top contributors
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Professor of medicine and deputy director of the Desmond Tutu HIV Centre at the Institute of Infectious Disease and Molecular Medicine, University of Cape Town
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Health Systems Researcher, Makerere University
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Senior lecturer in Paediatrics and Child Health, Stellenbosch University
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Honorary Research Associate, Centre for Infectious Disease Epidemiology and Research, University of Cape Town
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Research Professor, Perinatal HIV Research Unit and President, South African Medical Research Council
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Ezintsha, Faculty of Health Sciences, University of the Witwatersrand, University of the Witwatersrand
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Public Health Medicine Specialist, University of the Witwatersrand
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Research Fellow, Wits School of Public Health, University of the Witwatersrand
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Professor: Health and Population Division, School of Public Health, University of the Witwatersrand
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Head: Cell Biology, Centre for HIV and STIs, National Institute for Communicable Diseases
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Associate Professor and Director of the Centre for Infectious Diseases Epidemiology and Research, University of Cape Town
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Assistant Professor, Harvard University
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University of the Witwatersrand
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Assistant Professor, Africa Health Research Institute (AHRI)
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Assistant Professor, Family Health Care Nursing, University of California, San Francisco
