At the Third International Summit on Human Genome Editing, experts gather to discuss the path forward for CRISPR and other gene-editing technologies
DNA editing has the capacity to treat many diseases, but how to do this safely and equitably remains unclear.
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André O. Hudson, Rochester Institute of Technology and Gary Skuse, Rochester Institute of Technology
Following the controversial births of the first gene-edited babies, a major focus of the Third International Summit on Human Genome Editing was responsible use of CRISPR.
More people moved into Scandinavia in Viking times than at any other time period analysed in the study.
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DNA analysis reveals a large migration of people into Scandinavia during Viking times.
Statistical pitfalls in GWAS can result in misleading conclusions about whether some traits (like long horns or spotted skin, in the case of dinosaurs) are genetically linked.
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Richard Border, University of California, Los Angeles and Noah Zaitlen, University of California, Los Angeles
People don’t randomly select who they have children with. And that means an underlying assumption in research that tries to link particular genes to certain diseases or traits is wrong.
Over half of the human genome contains repetitive DNA sequences whose functions are still not fully understood.
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Two decades after the ‘full’ human genetic code was released to global fanfare, researchers have finally filled in the blanks that made up 8% of the sequence, thanks to recent advances in genome sequencing.
A complete human genome, seen here in pairs of chromosomes, offers a wealth of information, but it is hard connect genetics to traits or disease.
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The first full human genome was sequenced 20 years ago. Now, a project is underway to sequence 1 million genomes to better understand the complex relationship between genetics, diversity and disease.
A new finding in mice rewrites the textbook explanation of the male sex-determining gene, Sry. It might also help us better understand how males and females come to be.
Early proponents of genome sequencing made misleading predictions about its potential in medicine.
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Genome sequencing technologies have transformed biological research in many ways, but have had a much smaller effect on the treatment of common diseases.
Genetic studies need to be more diverse.
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Four months ago a researcher claimed he had used the tool CRISPR to edit the genomes of twin girls. Now prominent researchers and ethicists are calling for a temporary halt to this sort of work.
Indigenous Australians must be involved in research around provenance and country. Here, representatives of the Willandra Aboriginal Elders visit the Griffith University ancient DNA laboratory.
Renee Chapman
Museums around the world hold remains of Aboriginal people that were often taken without permission and in the absence of accurate records. New DNA methods may help return these items to country.
Jiankui He claims he has used CRISPR to edit the genomes of twin girls.
Merlin Crossley
The world seemed to be inching forward with CRISPR gene editing technology – but suddenly the forbidden fruit has been plucked, and some even worry that the CRISPR tree has been cut down.