While resurrecting dinosaurs may not be on the docket just yet, gene drives have the power to alter entire species.
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As genetic engineering and DNA manipulation tools like CRISPR continue to advance, the distinction between what science ‘could’ and ‘should’ do becomes murkier.
The red mangrove is among the species already selected for genome sequencing.
The African BioGenome Project is a pan-African project that seeks to sequence Africa’s endemic and indigenous plants and animals.
Over half of the human genome contains repetitive DNA sequences whose functions are still not fully understood.
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Advances in technology have enabled researchers to sequence the large regions of repetitive DNA that eluded the Human Genome Project.
For patients, often children, with rare diseases, getting a diagnosis is difficult and time-consuming.
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Record-breaking technology can sequence an entire human genome in a matter of hours. The work could be a lifeline for people suffering from the more than 5,000 known rare genetic diseases.
Crystal jellyfish contain glowing proteins that scientists repurpose for an endless array of studies.
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Three pioneering technologies have forever altered how researchers do their work and promise to revolutionize medicine, from correcting genetic disorders to treating degenerative brain diseases.
Two decades after the ‘full’ human genetic code was released to global fanfare, researchers have finally filled in the blanks that made up 8% of the sequence, thanks to recent advances in genome sequencing.
A complete human genome, seen here in pairs of chromosomes, offers a wealth of information, but it is hard connect genetics to traits or disease.
The first full human genome was sequenced 20 years ago. Now, a project is underway to sequence 1 million genomes to better understand the complex relationship between genetics, diversity and disease.
The achievement didn’t live up to the hype, but it has illuminated new areas of ‘genetic dark matter’.
Early proponents of genome sequencing made misleading predictions about its potential in medicine.
Genome sequencing technologies have transformed biological research in many ways, but have had a much smaller effect on the treatment of common diseases.
Nearly 20 years ago, Bill Clinton said that sequencing the human genome would give us a “new power to heal”.
Smaller research teams conduct more disruptive research; a new study could change research funding allocations.
A new study in Nature finds that large research teams develop recent ideas, while small teams conduct more disruptive and innovative research.
When the Human Genome Project completed its work in 2003, the entire human genome was published in book form.
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In 2003 the Human Genome Project “cracked the code of life”, yet parts of our DNA remained unidentified. A new study fills out our genetic blueprint by using a nanotechnology-based technique.
A tumor under the microscope.
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Cancer researchers dream of offering personalized treatments to patients. Can they get there using the same math that drives Netflix recommendations?
People get suspicious when ethically fraught science is discussed behind closed doors.
DNA image via www.shutterstock.com.
A recent closed meeting about building synthetic genomes raised suspicions about just what scientists were planning, away from the public eye.
Pipette tips with reaction mixture to amplify DNA.
It seems like a no brainer to edit out genetic disease…until we pause to consider what would be lost.
Unlocking the sequence.
The compact system that can cut the process of sequencing the Ebola virus from weeks to days.
The Human Genome Project was just the beginning. The Epigenome Roadmap is now telling us how all these genes switch on and off in different parts of the body, and how they go wrong with disease.
There’s still a lot we don’t know about how various genes are switched on and off. But a new project is seeking to shed light on the complex world of epigenetics.
Precision medicine delivers treatment based on the particular variant of the disease by taking the genetic make-up of the ill person into account.
Hidden among all the other announcements in last week’s State of the Union address by US President Barack Obama was a promise to fund a new “precision medicine initiative”. The president said it would…
Knowing your DNA will is not a panacea.
Walter Gilbert won the Nobel Prize in 1980 in Chemistry for his contribution to sequence DNA, or “determination of base sequences in a nucleic acid”. Mohit Kumar Jolly, researcher at Rice University and…
X-ray of hands with rheumatoid arthritis.
“Arthritis is for old people, right?” This is an outdated view of a spectrum of diseases that affect people of all ages in the population. In the past decade, there has been a revolution in the understanding…