The animal studies are promising but early research in humans show mixed results. Here’s what we know so far.
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Some women who use drugs like Ozempic have reported unexpected pregnancies. What’s going on?
Does weight come back when you stop taking drugs like Ozempic? Are these medications simply another (expensive) form of yo-yo dieting? Here’s what we know so far.
We don’t tell people taking statins to treat high cholesterol or drugs to manage high blood pressure they’re cheating or taking the easy way out. Nor should we when people take drugs like Ozempic.
In Australia, Ozempic is only approved to treat diabetes but doctors are prescribing it ‘off label’ for weight loss. Compounding pharmacies have also been making their own versions to meet demand.
Ozempic generated A$21 billion of sales in 2023 alone. So how was it developed? And how are its new competitors, Mounjaro and Zepbound, different?
Early on we heard a lot about the potential benefits of drugs like Ozempic. Now we’re hearing more about the risks. But what does the latest evidence say?
The demand for off-label weight loss drugs like Ozempic is concerning, because of the impact on weight stigma and the health risks of unsupervised weight loss, including developing eating disorders.
Weight loss and diabetes drugs target regulatory pathways involved in metabolism that the microbes in your gut and certain molecules from food already play a key role in regulating.
Medications can play an important role in weight management, but not at the expense of overall nutrition. And healthy lifestyle habits are also key.
When people stopped taking one of the new weight-loss jabs they regained around 60% of their lost weight.
People who are obese, as well as those who are overweight and have weight-related issues, may soon be able to ask their doctor for a prescription.
In trials, Mounjaro was shown to be more effective than Ozempic in managing type 2 diabetes.
The Conversation has been following the trials and tribulations of semaglutide (Wegovy) as it made its way from lizard venom to blockbuster drug.
From rat poison to explosives, many of the drugs we use have interesting origin stories.
Weight-loss jabs might help with certain heart conditions, but their benefit is being overstated.
Doctors once prescribed overweight people extracts of animal glands – either eaten raw or dried in pill form or injected – to treat their supposedly ‘sluggish glands’.
Ongoing shortages of the drug have been reported in the UK, Australi and Ireland.
Many processed foods strip carbs of their natural fibers. Eating foods with an ideal total carbohydrate-to-fiber ratio can help with weight management and improve overall health.
As the use of Ozempic, a drug for diabetes, slams into the mainstream as a weight-loss method, will the drug’s use impact our concept of fatness? And how does fatness intersect with race and class?
Top contributors
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Associate Professor of Metabolic Medicine, University of Surrey
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General Practitioner, PhD Candidate, Bond University
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Lecturer, Pharmacy, Aston University
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Associate Professor of Gastroenterology, School of Medicine, University of Washington
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Associate Lecturer, Sydney Pharmacy School, University of Sydney
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Associate Professor of the School of Pharmacy, University of Sydney
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Professor of Community Health and Wellbeing, The University of Queensland
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Career Development Fellow, University of Oxford
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Lecturer Pharmacy Practice, University of Sydney
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Professor of Exercise Science and Interim Dean of the School of Health Sciences, College of Charleston
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Senior Lecturer in Physiology, Anglia Ruskin University
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DPhil Candidate, Alzheimer's, University of Oxford
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Postdoctoral Researcher, School of Public Health, University College Cork
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Emeritus Professor of Reproductive and Periconceptual Medicine, The Robinson Research Institute, University of Adelaide
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Laureate Professor in Nutrition and Dietetics, University of Newcastle
