When regulatory agencies like Health Canada approve a new drug, they require the drug company to continue monitoring the product’s safety.
Health Canada continues to monitor newly approved drugs to determine if the benefits identified in the pre-market trials hold up to further scrutiny. Canadians need better access to that information.
It takes around 17 years for medical research to translate into clinical practice.
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In health care crises, researchers can avoid waiting for clinical trial results by using data from health care systems to analyze the effectiveness of treatments for COVID-19 and other illnesses.
Here’s why it’s taken so long to develop a vaccine for respiratory syncytial virus and what we can expect next.
Most clinical trials overrepresent young white males.
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Medicine works better when the treatments are tailored to fit each individual person’s biology and history. A first step is increasing diversity in clinical trials, but the end goal is precision medicine.
Constraining drugs to a single function in the body may be limiting their full potential.
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Despite technological advancements, many challenges remain in getting a drug from lab to pharmacy shelf. Reframing what is a “medicine” could expand treatment options for researchers and patients.
Creating a safe space for patients to ask questions and provide fully informed consent could help increase clinical trial recruitment.
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Overcoming the access barriers and biases that underrepresented and underserved communities face could not only improve research participation but also improve care.
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In silico clinicial trials have the potential to speed up trials and cut costs.
A nurse prepares medication for a patient in the TACTIC-R clinical trial at Addenbrooke’s Hospital in Cambridge, England, May 21, 2020.
What prompts healthy volunteers to take part in clinical research? And how are they protected?
President Joe Biden tested positive for COVID-19 on July 21, 2022, but was reportedly feeling well enough to work and take calls, as seen in this photo released by the White House.
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According to a letter from Biden’s doctor, the president has a runny nose, mild fatigue and a slight cough. The letter also noted that Biden began taking an antiviral drug the morning he tested positive.
About 8 million U.S. children have received two shots of COVID-19 vaccine and are now eligible for a third.
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The COVID-19 vaccines continue to be effective against severe illness leading to hospitalization and death in all age groups, including children ages 5 to 11.
Dozens of coronavirus vaccines are in clinical trials in the U.S.
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Existing coronavirus vaccines are not as effective against newer variants of the virus. Two vaccine experts explain how new vaccines currently in development will likely offer better protection.
Our study found a better way to treat eye problems in Indigenous communities – and some key considerations for undertaking culturally safe clinical trials.
Two Australians with bipolar have been successfully treated with poo transplants, allowing them to come off, or reduce, their medications. Here’s where the science is up to.
The majority of drug failures are attributed to lack of clinical efficacy and high toxicity.
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Drug development is a long and costly process that often ends in failure. Improving the way potential drug candidates are optimized could help boost success rates.
COVID-19 vaccines and treatments aren’t societal silver bullets when health disparities persist.
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Vaccines and medical treatments can only go so far in an unequal society. Facing the ongoing history of racial discrimination and bias in the US would help end the pandemic.
Understanding how much protection a vaccine offers is not as simple as it sounds.
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For a number of reasons, as time goes on vaccines become less effective. So how do researchers calculate how well vaccines are working?
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Emotive claims, like COVID vaccination being unethical or coercive, are more likely to be shared on social media. But we can fight back.
Nearly 80% of participants in FDA-reviewed research trials live in foreign countries.
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Regulatory loopholes for research conducted off US soil allow for questionable trials and misleading data to slip under the FDA’s radar.
A new study suggests the market alone will not deter or punish pharmaceutical companies whose products turn out to have adverse effects after they have been approved.
The path to using old drugs for COVID is full of potholes. So why are we using the same old flawed methods when we actually know what works?