Two hurdles mRNA drugs face are a short half-life and impurities that trigger immune responses.
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The COVID-19 pandemic demonstrated the promise of using mRNA as medicine. But before mRNA drugs can go beyond vaccines, researchers need to identify the right diseases to treat.
mRNA vaccines are very safe, but this problem needed to be fixed for future mRNA therapies.
One of the advantages of mRNA is its scalability.
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From COVID-19 vaccines to cancer treatments and beyond, the flexibility of mRNA-based therapies gives them the potential to prevent and treat many types of diseases.
Considered a pipe dream not too long ago, research on RNA therapeutics is progressing rapidly. Now a new manufacturing protocol will help researchers to advance the technology.
The goal of mRNA technology is to harness the power of the cell to potentially prevent infections and treat diseases.
Basic research often involves lab work that won’t be appreciated until decades down the line.
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The winners of the 2023 Nobel Prize in physiology or medicine made a discovery that helped create the COVID-19 vaccines. They couldn’t have anticipated the tremendous impact of their findings.
Karikó and Weissman first began working together in 1985.
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The prestigious prize was awarded to Dr Katalin Karikó and Dr Drew Weissman from the University of Pennsylvania.
Immunotherapies, such as cancer vaccines, help train the immune system to fight off cancer.
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This study further highlights the potential of mRNA vaccines in cancer treatment.
Vaccines help protect farm animals from various diseases.
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While mRNA vaccines are designed to last longer in the body than mRNA molecules typically would, they are also tested to ensure they are eliminated from livestock long before milking or slaughter.
Cancer vaccines are an emerging personalised treatment for cancer. Using the same mRNA technology as COVID vaccines, they stimulate the immune system to destroy cancer cells.
Here’s why it’s taken so long to develop a vaccine for respiratory syncytial virus and what we can expect next.
A team from the University of Tours and INRAE is working on the development of an innovative nasal vaccine against Covid, in spray form.
Vaccination is often combined with an injection. It can also take the form of a nasal spray: an approach that is still rare, but which could be effective against Covid. Here’s why.
Broad protection from a universal flu vaccine could replace seasonal flu shots.
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Annual flu vaccines are in a constant race against a rapidly mutating virus that may one day cause the next pandemic. A one-time vaccine protecting against all variants could give humanity a leg up.
Moderna is testing an mRNA vaccine in combination with pembrolizumab to treat melanoma.
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Preventive and therapeutic vaccines both train the immune system to fight disease, but they are used in different ways.
XBB.1.5 is rapidly spreading across the globe and will likely become the next dominant COVID-19 subvariant.
The XBB.1.5 subvariant — nicknamed ‘Kraken’ — is arguably the most genetically rich and most transmissible SARS-CoV-2 Omicron subvariant yet.
The UK government announced that it is partnering with BioNTech to trial personalised cancer vaccines.
As the virus that causes COVID evolves, keeping up with it remains a challenge for variant-specific vaccines. The booster you can get now is the best one to get.
It is safe to get the newly formulated COVID-19 booster shot and the flu shot at the same time.
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When COVID-19 and the flu co-infect, it’s ‘flurona.’ But such cases are rare, and there are effective ways to protect yourself from both viruses.
Funding research is essential to meet future health challenges.
Canadian scientists have made significant contributions during the pandemic response, including vital roles in developing COVID-19 vaccines. But underfunding puts the future of science in Canada at risk.
In a matter of days, eligible people will be lining up to receive the newly formulated booster shot.
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The CDC’s endorsement of the reformulated COVID-19 booster shots represents a major step in the effort to get more Americans boosted.