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Articles on Drug development

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We’re in a protracted war against superbugs because we’ve overused existing antibiotics: a key weapon against disease. Nomadic Lass/Flickr

We need new antibiotics to beat superbugs, but why are they so hard to find?

We’ve heard a lot lately about superbugs – bacteria that are resistant to current antibiotics. But as the threat of superbugs continues to rise, the number of new treatments available has flatlined. This…
Overcoming gaps in medical funding. nakrnsm

Trials funded by rich patients could help find cures for us all

Disease can affect any person, rich or poor. While your bank balance can’t really protect you from getting sick, it could potentially buy you – and many other patients – access to a better treatment for…
Who’s going to pay for this? image via www.shutterstock.com

Development of new drugs is threatened by budget cuts

Foundation essay: This article is part of a series marking the launch of The Conversation in the US. Our foundation essays are longer than our usual comment and analysis articles and take a wider look…
A Liberian nurse disinfects a looted mattress taken from an elementary school that was used as an Ebola isolation unit in West Point, Monrovia, Liberia. AHMED JALLANZO/EPA

Epidemic ethics: four lessons from the current Ebola outbreak

The extent of the current Ebola virus outbreak in West Africa has belatedly focused the attention of non-governmental organisations, local and Western governments, and international media. What we haven’t…
Major pharmaceutical companies have shown little interest in developing effective treatments for illnesses such as Ebola virus disease. AAP Image/David Crosling

How Western national interest drives Ebola drug development

Ebola virus disease typically only occurs in rural and remote areas among resource-poor populations. Until the large, recent outbreak in West Africa, cases of the illness were a rarity. So the fact that…
Cancer drugs like trastuzumab may not have been approved under the proposed rules. RedAndr

NHS watchdog changes could endanger new cancer drugs

The National Institute for Health and Care Excellence (NICE) has published new draft proposals laying out major changes to the way it assesses whether new medicines offer value for money for the NHS. These…
Pills, spills and development aches. ep_jhu

Why there may be fewer truly new drugs hitting the market

Developing new drugs is hard and expensive. The lengthy process from initial discovery to the market is some times compared to the difficulty of putting a person on the moon. Despite accusations that the…
Doesn’t have to be like this for too long. lucasfrasca

Insulin pill may soon be a reality

Daily jabs of insulin are a painful reality for many with diabetes. That may change if researchers who have successfully tested oral insulin in rats are able to replicate those results in humans. Nearly…
Still could go one way or another. Harsh Vardhan

Expert warns caution over possibility of Alzheimer’s pill

It has been described as a historical “turning point” in Alzheimer’s treatment - the first time a chemical has been found that can halt the death of brain tissue in a neurodegenerative disease, and could…
Many of the colours in medieval stained glass are produced by nanoparticles. Quinn Anya

Nanotechnology in medicine isn’t just about size

While scientists develop new drugs to treat a multitude of conditions, nanotechnology is pushing the boundaries of how we deliver them to patients - targeting delivery to cancer cells and giving a drug…
Feeling fruity: the amoeba Dictyostelium discoideum forms ‘fruiting bodies’ Robin Williams

Want a new epilepsy drug? Bring on the amoebas

Many therapeutic drugs and toxins affect us without us knowing exactly how. We know, for example, that Epilim, or sodium valproate, one of the most highly prescribed medicines for epilepsy can prevent…
The researcher had tampered with data from pre-clinical trials of an anti-cancer drug. Esther/Flickr

UK researcher sentenced to three months’ jail for faking data

A British scientist convicted of scientific fraud last month for falsifying research data has been sentenced to three months jail. Steven Eaton is the first person to serve time under the UK’s Good Laboratory…
There are no magic bullets in the antibiotic pipeline that will eradicate the superbugs. Alessandro Pinna

New antibiotics: what’s in the pipeline?

Bacteria are one of the most successful colonisers of the planet. They can be found in almost all environments we know – from the deepest oceans to acid lakes, and inside and on our bodies. And the history…
The days when there was always a new antibiotic just around the corner to treat the latest superbug are long gone. Ralph Keating

Unblocking the pipeline for new antibiotics against superbugs

Most experts considering the subject agree that the antibiotic development pipeline is not sufficient by a long shot. The days when there was always a new antibiotic just around the corner to treat the…

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