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Articles on Drug development

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A lab technician holds a vial of a COVID-19 vaccine candidate during testing at the Chula Vaccine Research Center, run by Chulalongkorn University in Bangkok, Thailand on May 25, 2020. (AP Photo/Sakchai Lalit)

Explainer: How clinical trials test COVID-19 vaccines

Will a vaccine for COVID-19 be safe? Animal testing, human clinical trials and post-approval surveillance give us good grounds to believe that a future approved vaccine will work and be safe.
The scope and length of vaccine testing experiments usually mean decade-long timelines for development. (Pixabay)

Fast COVID-19 vaccine timelines are unrealistic and put the integrity of scientists at risk

It usually takes 10 years for a new vaccine to complete clinical trials, but we’ve been promised a COVID-19 vaccine in 12 to 18 months. Even if such fast-tracked development is possible, is it wise?
Globally, billions of dollars in public funds have been committed for COVID-19 vaccine development. It’s crucial that the resulting vaccine be accessible to all. (Shutterstock)

Coronavirus vaccine must be affordable and accessible

Canada is investing millions to develop COVID-19 treatments, but there are no safeguards to ensure that those vaccines and medications will be affordable and accessible to the people who need them.
Venom from box jellyfish causes extreme pain and tissue damage. Massive exposure can cause death. from www.shutterstock.com

How we used CRISPR to narrow in on a possible antidote to box jellyfish venom

Box jellyfish stings are excruciating and occasionally deadly. We have identified a common, cheap drug that is already on the market and which could be a treatment candidate with further development.
Pharmaceutical companies have traditionally been the ones to develop drugs. But for rare diseases university researchers may play a role. LeoWolfert/Shutterstock.com

Drug development is no longer just for Big Pharma. Researchers at Bio-X explain

Developing drugs is typically the domain of large pharmaceutical companies. But here is an example of drug development for a rare pediatric brain cancer that was done in a university setting.
Scientists are now using evolution to create designer proteins for therapies and industrial processes. Johan Jarnestad / The Royal Academy of Sciences

2018 Nobel Prize for chemistry goes to scientists who learned to ‘hack’ evolution in the lab

Nature doesn’t always make the things we need so three Nobel Prize winners figured out how to fast-track evolution in the lab to create medicines, biofuels and industrial chemicals for modern life.

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