A biologist explains what proteins do in viruses, how they interact with human cells, how the vaccine delivers mRNA into the cell and how antibodies protect us.
A biologist explains where proteins come from and what role the 20,000 or so proteins in your body play in keeping you alive and kicking.
SARS-CoV-2 mutates all the time, creating new variants. That doesn't automatically mean it's getting more harmful or better at spreading.
Scanning through billions of chemicals to find a few potential drugs for treating COVID-19 requires computers that harness together thousands of processors.
Researchers are starting to understand why the bones of diabetic people are more prone to fractures.
Pizza might seem like a simple food, but it's uniquely equipped to excite our brains and thrill our taste buds.
AMPK is normally a tumour suppressor. But once cancer arises, AMPK becomes a tumour promoter, enhancing the survival of cancer cells. Understanding this could help create drugs that inhibit AMPK.
The glue that gives spider webs their stickiness is a form of spider silk protein. Researchers can imagine cool uses for a synthetic version – but had to wait for the tricky glue gene to be sequenced.
When two proteins interact with each other they behave in their own molecular lives.
The unique way that human proteins change after they are copied from our DNA gives scientists clues about what causes human disease.
Proteins guard their secrets closely, but once you get them to "sing", there's an enormous amount to learn.
A core idea in molecular biology is that one gene codes for one protein. Now biologists have found an example of a gene that yields two forms of a protein – enabling it to evolve new functionality.
Some spiders produce silk than can actually be stronger than steel and 50 times as light.
Researchers use an algorithm designed to help robots move to figure out what's possible when designing new molecules in a promising class of pharmaceuticals.
One big challenge for gene therapies is delivering DNA or RNA safely to cells inside patients' bodies. New nanoparticles could be an improvement over the current standard – repurposed viruses.
By exploiting the way yeast cells mate, researchers have figured out a quicker, easier way to identify on- and off-target drug interactions.
The 2017 Nobel Prize in chemistry goes to three scientists who revolutionized biochemistry by inventing a technology that can image the molecules of life without destroying them.
Inserting a random DNA mishmash into a plant or bacterium directs it to make a novel protein. Sifting through the resulting molecules, researchers may find ones have medical or agricultural uses.
How do anesthetics work, and what makes for an ideal anesthetic? It's not as mysterious as once believed, and there's a gas that ticks all the boxes for a perfect anesthetic: xenon.
Rather than being designed by chemists, this class of pharmaceuticals is produced by living cells. Here's where they come from and how they work.