Simple and inexpensive gene-editing technology such as CRISPR has made the creation of genetically modified organisms much easier. But could nature still keep the upper hand?
Editing DNA has the potential to treat disease by repairing or removing defective genes.
William Isdale speaks with University of Queensland Professor Peter Koopman about CRISPR technology.
Laboratory mice are among the first animals to have their diseases treated by CRISPR.
tiburi via Pixabay.com
A new research paper reports dangerous side effects in CRISPR-edited mice. Some scientists are pushing back, placing blame for the unwanted mutations on the experiment, not the technique.
Human genome editing raises a lot of questions.
Gene sequence image via www.shutterstock.com.
A new report from the National Academies of Science and Medicine outlines conditions that have to be met before gene editing that results in heritable genomic changes can be considered.
Gene therapy is growing in its capabilities, but there should be limits to its use.
A report released by the US National Academies of Science and Medicine underscores the potential of gene editing and acknowledges the sensitivities in managing the ethical dimensions.
Taking the deadly bit out of mosquitoes.
Flickr/Erik F Brandsborg
It's possible to alter the make-up of a species such as a mosquito's ability to pass on the deadly malaria parasite. But we need to consider the pros and cons of such gene editing technology.
Human oocyte in vitro fertilization.
Medical tourism for assisted reproductive technologies raises a host of legal and ethical questions.
CRISPR uses segments of bacterial DNA that can make targeted cuts in a genome when paired with a specific guide protein.
Controversy over a Chinese study that used CRISPR-Cas9 gene-editing technology shows how the West still looks at the East through the lens of Orientalism.
Will China be the first to genetically enhance future generations?
Regulations, funding and public opinion around genetically enhancing future generations vary from country to country. Here's why China may be poised to be the pioneer.
A patent has far-reaching implications for future research.
U.C. Berkeley and the Broad Institute are fighting to control the patents on the revolutionary gene-editing technology. But there's a lot more at stake than just who gets the credit and licensing fees.
We’re talking about a lot of seeds.
Great Divide Photography
The concerns about genetically modified foods are well known. But when we look at population and climate projections, what happens if we don't use them to increase our food supply?
New research suggests how we could prevent genetically modified organisms from surviving - and potentially spreading - in the wild.
A snip here, but not a snip there?
DNA image via www.shutterstock.com
The International Summit on Human Gene Editing drew a distinction between editing an individual's body cells and editing germline cells that would pass changes to future generations. Does that make sense?
Image of babies via www.shutterstock.com.
As we consider the ethics of human gene editing, we need to understand what can and can't be meaningfully edited.
Gene editing allows us to eliminate any misspellings, introduce beneficial natural variants, or perhaps cut out or insert new genes.
Should the gathering of experts from around the world that's considering the scientific, ethical, and governance issues linked to research into gene editing ring alarm bells?
New genetic technology could change the DNA of entire species to prevent them from spreading diseases.
Tomas Lindahl, pictured here in the lab, along with Paul Modrich and Aziz Sancar, received the Nobel Prize for Chemistry.
The recipients of this year's Nobel Prize for Chemistry showed that DNA is far from static. Rather, it is bombarded by damaging forces, but our bodies know how to repair these precious strands.
Gene editing has many potential applications that are not discussed enough.
Despite predictions, the CRISPR/Cas9 gene editing technique didn't win the Nobel Prize. But with the technology nevertheless taking off, it is time we start having an informed public debate about it.
The red Cas9 nuclease protein uses a blue guide RNA sequence to cut yellow DNA at a complementary site.
CRISPR-Cas9 via www.shutterstock.com
Until more is understood, it's sensible to limit experimentation that would make changes to germ line cells that would be passed on to future generations.
A powerful new genetic engineering technique allows scientists to precisely cut out and replace DNA in genes.
Jennifer Doudna/University of California Berkeley
Leading researchers have called for a ban on using a precise gene-editing technology on humans. How can CRISPR advance science and why is it raising concerns?