Articles on Clinical trials

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When drug companies and drug regulators, such as Health Canada, sit down together at “pre-submission meetings” this may have a negative impact on public health. (Shutterstock)

Health Canada and Big Pharma: Too close for comfort

Drug companies have a job to do and so does Health Canada. When the relationship becomes murky, the public are at risk.
An MRI image of the brain. SpeedKingz/Shutterstock.com

An unexpected pathway to treating neurodegenerative diseases

Not all drug development needs to start from scratch. Sometimes researchers discover that a drug developed for one disease can be used for another. Here a cancer drug may show promise for dementia.
Research published in Science Translational Medicine in February 2019 used a virtual patient to test the drug, Fevipiprant. (Shutterstock)

A new drug promises to lower risks of asthma attack

Asthma affects around 339 million people worldwide. A new drug promises to lower risks of asthma attack and may eventually allow patients to reduce their dependence on steroids.
Canadian finance minister Bill Morneau announced funding for a new Canadian Drug Agency in the 2019 Federal Budget. Here he speaks at a press conference in Toronto, March 20, 2019. THE CANADIAN PRESS/Cole Burston

Federal budget: A Canadian Drug Agency and rare disease funding are not enough

A new agency and money for drugs for rare diseases are only very partial steps on the road towards what Canada really needs: a national pharmacare plan.
Ear infections are no fun. The OSTRICH clinical trial looked at whether oral steroid medications might help. from www.shutterstock.com

How researchers assess whether medications work

Clinical trials can assess impact of a medication on a disease. The ideal design is 'blind' – when the researchers and participants do not know who is assigned to the different treatments.
Antidepressants bring in almost $17 billion a year for the pharmaceutical industry, and yet science shows their benefit to be small. Natural therapies such as diet, exercise, light therapy and cognitive behavioural therapy are just as effective. (Shutterstock)

Why natural depression therapies are better than pills

These four “natural” therapies for depression have rigorous, peer-reviewed scientific studies to support their use.
Early-onset Alzheimer’s disease presents unique challenges, when a patient is still working or parenting children.The personality changes involved can result in job loss or divorce before a diagnosis is made. (Shutterstock)

Is that ‘midlife crisis’ really Alzheimer’s disease?

Alzheimer's disease affects many people under the age of 65. The 'young-onset' version of the disease is often misdiagnosed as depression or dismissed as a midlife crisis.
This African woman suffers from an autoimmune disease called vitiligo which causes the loss of skin pigment. By andreonegin/shutterstock.com

New treatment in the works for disfiguring skin disease, vitiligo

An autoimmune disease called vitiligo causes white spots to appear on the body, in some cases completely erasing an individual's pigmentation. But a new therapy is on the horizon.
Eczema, which is common in babies, is itchy and painful. silentalex88/Shutterstock.com

Applying live bacteria to skin improves eczema

In this clinical trial, the first of its kind, physicians explore whether directly applying a 'good' strain of bacteria to the skin can heal eczema
There are currently no effective treatments for Alzheimer’s disease, which causes may elders to live their last years without recognizing their loved ones, and unable to care for themselves. (Shutterstock)

Can the healthy brain offer clues to curing Alzheimer’s?

Study of the "memory centres" of the brain in adults offers hope for detecting Alzheimer's disease earlier -- before the onset of memory loss.

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