Spanish flu killed more people than the Great War that preceded it. And tuberculosis even more than that.
Here we explore our past and present struggles with four of the most significant infectious diseases human beings have faced, and some of the progress we've made in prevention and treatment.
In Australia we still vaccinate against polio, but not tuberculosis. Why, and how do we decide?
Vaccinating against an infectious disease can stop once the threat of future transmission is deemed sufficiently low.
US President Donald Trump is threatening drastic cuts in foreign aid.
The proposed foreign aid cuts by US President Donald Trump will have a devastating impact on healthcare in Africa.
TB most commonly causes pneumonia. Sick people experience cough, fever, sweats and weight loss, usually over weeks to months.
In Australia, there are around 1200 to 1300 cases of tuberculosis each year which means we are among the lowest-risk countries in the world.
Scientists have struggled to diagnose TB in people with compromised immune systems because of the low levels of the bacteria in their body.
To tackle TB a dynamic change in discourse is needed. The focus must be on how to respond to emerging complexities the disease presents.
Shortening the treatment period has become a top priority within TB research but studies to date have been unsuccessful.
Antibiotics that were not originally earmarked to treat TB have shown the first signs of effectiveness and could be added to the much-needed arsenal of drugs to fight the deadly disease.
The age profile of people living in Africa is changing - they are living longer.
The burden of communicable disease is declining in Africa and life expectancy is increasing. But non-communicable diseases like diabetes, cardiovascular disease and cancer are wreaking havoc.
Migration patterns can have an impact on health and policies.
When people migrate they can end up worse off when it comes to getting access to health care. Analysing migration trends can help drive local public health policy towards the correct targets.
Meshack Mavuso played the role of ‘The Man with the Green Blanket’ in ‘Marikana the Musical’
Two musicals set in working class mining communities -- one in the UK and the other in South Africa -- have diametrically opposed messages: one of hope; the other, despair.
Africa Centre for Population Health
A new centre in South Africa will work to significantly reduce emerging HIV and TB co-infections.
One-third of the world’s population is latently infected with the bacteria that cause tuberculosis.
Scientists have found proteins in the body that promote lung inflammation which helps the bacteria that causes TB to spread throughout the lung.
South African scientists have found a way to single out the problematic parts of the bacteria causing TB that results in drug resistance.
African scientists have developed and patented a test for TB that overcomes two major challenges with current methods: it delivers quick results and is much cheaper.
Understanding what causes diseases is a life-and-death matter. It is a complicated issue that has generated a great deal of debate in the medical community.
Antiquated methods of treating TB included sunbathing. The modern-day equivalent is vitamin D supplements.
In countries such as South Africa with a high burden of TB and HIV, vitamin D could be an extremely effective and cheap weapon to include in the arsenal against TB and HIV.
A pair of lungs infected with TB.
There is an increasing focus on alternative treatment strategies, developed to treat other diseases and conditions but re-purposed to tackle TB.
A new technique could help uncover previously unknown genetic factors contributing to susceptibility to TB.
Although one third of the world's population have the TB bacterium, the disease only develops in 10%, which may be linked to genetic factors.
Eradicating TB across the globe by 2035, as the World Health Organisation hopes to do, will only take place if the global funding and will improves.
More than 1.5 million people die of tuberculosis across the world every year. Although testing and screening has improved and more drugs are available, it is not enough to conquer the scourge.