Genetic differences, drug interactions and inflammation can affect how well drugs work in the body.
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The same dose of a drug can have varying degrees of effectiveness and safety depending on how well the liver can metabolize it.
A cross section of lab-grown human liver tissue. The green shows the network of blood vessels.
Velazquez et al. Cell Systems
New strategy helps build synthetic organs from scratch. This enabled the researchers to grow functioning liver tissue in the lab that could be transplanted into mice with liver disease.
Our circadian rhythm is an important aspect of our health.
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Frequent disruption of our internal ‘body clock’ is linked to type 2 diabetes and obesity.
Obesity is one of the risk factors for non-alcoholic fatty liver disease.
Almost all drugs are tested in living animals before human clinical trials. But most of the time what works in mice doesn’t work in humans. That’s why lab-grown human livers may be so valuable.
People of color face more obstacles on the path to an organ transplant.
Although certain racial minorities are more likely to be diagnosed with organ failure, they are less likely to be transplanted. What’s behind the gap?
Significant new insights are emerging for the treatment of malaria, and eventually its eradication.
Many countries around the world can’t meet the demand for donor organs.
Religious and cultural beliefs play a role in the country’s organ donor shortages. But these factors alone grossly oversimplifies the issue.
More than a year after a groundbreaking liver transplant doctors still can’t say if the recipient is HIV-positive or not.
A liver transplant from an HIV-positive living donor to an HIV-negative recipient is possible, but there are still gaps in our knowledge.
No mother wants their baby to develop jaundice, but it turns out that they should probably be grateful.
Keep the buzz. Lose the hangover.
A new pill may lower blood alcohol levels, helping a hangover and preventing alcohol overdose deaths.
The health scare surrounding nanoparticles might lead to people abandoning formula unnecessarily, with serious impacts on babies’ health.
A widely publicised study that cast doubt on the safety of milk formula was misleading, based on dubiously reported studies and may have serious consequences.
Can the liver actually be cleansed?
Does the liver really respond to an over-the-counter product that claims to ‘detoxify’ or ‘heal’ its function?
A lot of cancer researchers shy away from researching cancers where they can’t see a clear research path going forward 10 or 15 years, the author of the report said.
Pan American Health Organization-PAHO / World Health
Australia’s mortality rate for all cancers has dropped 28% in 20 years, new figures show, but progress has been slow in the fight against thyroid and pancreatic cancer, while the death rate from liver…
liver cells are known for their ability to regenerate but it’s difficult to replicate in the lab.
The liver is a special organ. Mature liver cells - or hepatocytes - have the capacity to continually divide and repair damage. But only so far. Excessive drinking and chronic liver disease, for example…
Circadian receptors have been discovered in the liver, as well as the brain. Circadian receptors – known as “the circadian…
The liver – an organ never before considered in weight management – can directly talk to the brain to control the amount…